The younger sister of actress Michelle Pfeiffer, DeDe Pfeiffer began making the casting rounds in 1984, just before Michelle matriculated to superstardom. As was the case of most celebrity siblings, the bulk of DeDe's film work has been in crime melodramas, horror films and direct-to-video offerings.
She has, however, been seen to good advantage in several A pictures, notably Into the Night (1985), Tune in Tomorrow (1990) and Falling Down (1993); in the opening scenes of 1991's Frankie and Johnny, DeDe has a piquant cameo as the cousin of the character played by her sister Michelle. In 1994, DeDe Pfeiffer was cast as Rachel Blanders, daughter of fortysomething actress Cybill Sheridan (Cybill Shepherd), in the popular CBS TV sitcom Cybill. ~ Hal Erickson, All Movie Guide. 